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May 25, 2009

Do twins born after IVF have a higher risk of health problems?

Filed under: Health Care — Tags: , — admin @ 3:49 pm

Twins conceived through in vitro fertilisation (IVF) and similar treatments are more likely to need neonatal intensive care and to be hospitalised in their first three years than naturally conceived twins, according to a new study.
What do we know already?

About 1 in 7 couples in the UK have difficulty conceiving at some time and seek specialist fertility treatment. Many have IVF or another form of assisted reproductive technology (called ART). These procedures involve harvesting eggs from a woman’s ovaries, fertilising them in the laboratory, and then transferring the embryo back into the woman’s womb or fallopian tubes.

In the UK, about 1 in 4 women have twins after conceiving through IVF and similar treatments. This happens when doctors use more than one embryo to increase the likelihood that the procedure will work.

In general, twins have a higher risk of problems such as low birth weight and premature delivery than singleton babies, regardless of how they were conceived. But until now researchers haven’t known whether twins born after fertility treatment such as IVF have an even higher risk of health problems.

To explore this issue, researchers have now done a large study looking at the post-birth care and hospitalisations of twins born in Western Australia between 1994 and 2000.
What does the new study say?

The researchers compared twins born through IVF and similar treatments with non-identical twins conceived naturally. They didn’t include identical twins because twins born as a result of IVF are usually non-identical and the researchers wanted to compare like with like.

Using government databases, researchers gathered information on 700 babies born as a result of IVF and similar treatments and 1,240 babies conceived naturally. When comparing these groups, they took into account several things known to increase the chance of problems at birth or soon after. For example, women who have fertility treatments tend to be older, which can increase the risk of premature delivery and other problems.

After making adjustments for these factors, the researchers found that twins born after IVF and similar treatments:

* Stayed longer in hospital than other twins at the time of their birth (an average of 12 days, compared with eight days)
* Had about a two-thirds higher risk of being admitted to neonatal intensive care
* Had a two-thirds higher risk of being admitted to hospital in their second year of life. They also had a slightly higher risk of needing hospital care in their first and third years, but the difference was small and could have been down to chance.

So is there something about IVF and similar treatments that increases the risk of problems at birth and beyond? Possibly, although other factors may be at work as well. For example, some women may have an underlying problem that makes it difficult for them to conceive and also affects their pregnancy. Also, parents who have a difficult time conceiving may be more anxious about their babies, and more likely to take them to hospital.

Even so, these findings should add a new note of caution to discussions between would-be parents and doctors about using more than one embryo during fertility treatment.
How reliable are the findings?

This study was well done overall, and its results should be fairly reliable. However, the researchers were only able to gather information on hospital treatments. So it’s possible that some babies had health problems but were treated elsewhere. Also, the researchers weren’t able to track whether women had used any other types of fertility treatments, such as drugs to stimulate the ovaries to produce eggs. Some research has suggested that these treatments might also lead to higher rates of hospital admissions after birth.
Where does the study come from?

The study was done by researchers in the UK and Australia, and it was funded by a grant from the National Health and Medical Research Council of Australia. It was published in a medical journal called Human Reproduction, which is owned by Oxford University Press.
What does this mean for me?

If you are thinking about having fertility treatment such as IVF, bear in mind that implanting more than one embryo greatly increases your chance of twins, and twins in general have a higher risk of problems, such as premature delivery. This study now shows that the risk of health problems may be even higher for twins conceived through IVF, and this risk may extend through the first few years of life.
What should I do now?

Many doctors advise against implanting more than one embryo during IVF and similar treatments, because of the problems associated with multiple births. But, ultimately, the decision is yours. Be sure to talk to your fertility specialist about all the risks and benefits of treatment, so you can make a decision that is right for you.
From:

Hansen M, Colvin L, Petterson B. Twins born following assisted reproductive technology: perinatal outcomes and admissions to hospital. Human Reproduction. Published online 20 May 2009.

To learn more, see our information on fertility problems.

© BMJ Publishing Group Limited (”BMJ Group”) 2009

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May 23, 2009

Will Americans stop buying drugs Online ?

Filed under: online pharmacy — Tags: — admin @ 8:10 am

There will always be a debate whether or not Americans would stop buying drugs online . Since its convenient and hassle free from using prescription and going through all the formality . Its more of a luxury to normal citizens to go for online pharmacy still. Even though government policy is against it people are bound to buy it through one of the medical store online.
I guess government should have more flexible approach while dealing with online pharmacies . As its important that normal American citizen shouldn’t have a hard time buying drugs waiting for weeks which they could do in a matter of day.

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May 22, 2009

Father appeals to his wife to return with their cancer-stricken son

Filed under: Health Care — Tags: , , — admin @ 4:32 am

SLEEPY EYE, Minnesota (CNN) — The father of a cancer-stricken 13-year-old boy whose mother has fled with him to keep him from undergoing chemotherapy appealed Thursday for her to bring him home.
Doctors say Daniel Hauser’s lymphoma responded well to a first round of chemotherapy in February.

Doctors say Daniel Hauser’s lymphoma responded well to a first round of chemotherapy in February.

“Please bring Danny home so that we can decide as a family what Danny’s treatment should be,” Anthony Hauser said, directing his halting comments to his wife, Colleen, as he stood in front of television cameras outside the family’s house.

“I know you’re scared and I feel that you left out of fear, maybe without thinking it all the way through,” he continued. “Danny is my son and the rest of the family is worried sick about Danny, how he is and how he’s going to come out.

“Please call me and let’s talk about how you can come back here and we can get this worked out, what’s best for Danny.”

The boy was diagnosed with Stage 2B Hodgkin’s lymphoma in January. The next month, he received a single course of treatment, which succeeded in shrinking a tumor in his chest but caused side effects that upset the family, doctors have said. Video Watch father urge the pair to come back »

Dr. Bruce Bostrom, the cancer specialist who oversaw that course of chemotherapy, told KARE-TV in Minneapolis that, without further treatment, Daniel’s odds of survival would plummet from 80 to 90 percent to about 5 percent.

Daniel’s second round of treatment was to have begun March 5, said the pediatric oncologist and associate professor at the University of Minnesota Medical School.
Don’t Miss

* Mother, son missing in forced chemotherapy case
* MayoClinic.com: Hodgkin’s lymphoma

In April, after the boy had not returned for the second course, Bostrom called the family and left a message threatening to report them for child neglect, he said.

Colleen Hauser returned his call, telling him she was seeking a second opinion. But the doctor who ultimately cared for the boy has said he was only treating his symptoms, not the cancer itself, Bostrom said.

So Bostrom reported the family to authorities, the first time he has taken such a step in 25 years of practice, he said.

“I think it’s our and my duty to do this,” he said.

Meanwhile, the opportunity to intervene is narrowing. “He’s now almost three months late, that’s why it has regrown,” Bostrom said, referring to another doctor’s interpretation of a chest X-ray that showed Monday the tumor had worsened.

“It means his cancer is back and he is in danger,” Bostrom said. “It could block his airway; he could develop life-threatening breathing problems and possibly even die from it. It could be within a few weeks or a month at the most, I would say.”

Hodgkin’s lymphoma is a cancer of the immune system. Stage 2B refers to the two areas of the body where Daniel has it — the chest and the neck — and the symptoms he has experienced: tumor, fatigue, weight loss and night sweats.

Authorities said Wednesday that Colleen and Daniel Hauser were near Los Angeles, California, perhaps en route to Mexico for more holistic treatment of his lymphoma.

Brown County, Minnesota, Sheriff Rich Offmann cited “reliable information” in making the announcement to reporters. The sheriff’s office issued a felony arrest warrant for Colleen Hauser on Thursday in an effort to “ensure extradition to Minnesota.”

Family spokesman Dan Zwakman said on Thursday that Anthony Hauser was not aware that his wife was taking the child.

“From all appearances,” Zwakman said, “it was a case of her decision by herself.” Video Watch what legal issues are at stake »

The boy and his mother were last reported seen Monday in Minnesota. When mother and son failed to show up at a court hearing Tuesday, Brown County District Judge John R. Rodenberg issued an arrest warrant for Colleen Hauser.

Court documents show that the doctors estimated the boy’s chance of five-year remission with more chemotherapy and possibly radiation at 80 percent to 95 percent.

But the family rejected standard treatment, opting instead for a holistic medical treatment based on Native American healing practices called Nemenhah.

In a written statement issued last week, an attorney for the parents said they “believe that the injection of chemotherapy into Danny Hauser amounts to an assault upon his body, and torture when it occurs over a long period of time.”

Dr. Sanjay Gupta, CNN chief medical correspondent, said he had no doubts about what to do.

“My advice would be to treat him, without question,” he said. “He has a very, very good chance of surviving, being cured and never having to deal with this again. As a doctor, as a fellow citizen, I would say he should be treated.” Video Watch Gupta discuss Daniel’s chances »

But Zwakman told CNN’s “American Morning” program Thursday that he knows five people who have been cured with natural healing.

“Yes, it’s happened many times,” he said. Video Watch Zwakman speak to CNN »

Mankato, Minnesota, lawyer Calvin P. Johnson, who identified himself as the Hauser family’s attorney, said Thursday that forcing treatment would constitute “assault and torture.”

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May 18, 2009

UCSB Relays for Cancer Research

Filed under: Health Care — admin @ 11:20 am

Students Enjoy Live Music, Games at Overnight Fundraiser

By Angel Rodriguez / Reporter

Published Monday, May 18, 2009

Issue 128 / Volume 89

Over a thousand Good Samaritans raised nearly $78,000 for the American Cancer Society this weekend by walking, running and jogging through the night at UCSB’s 6th annual Relay For Life.

Intended to support the fight against cancer and to commemorate the lives of cancer victims and survivors, the 24-hour relay saw over 1,400 participants crowd the UCSB track on Friday and Saturday. Live music, rap battles and games such as Bull Pong – a non-alcoholic version of Beer Pong played with Red Bull energy drinks – kept participants alert throughout the long hours of the night.

Event planner Katie LaValley, a fourth-year biological chemistry major, said she was astonished by how successful Relay for Life has become over the years.

“Six years ago we started with $1500 and one tent, and now look how we have grown,” LaValley said. “Despite the difficult recession occurring, people continue to contribute and fight against cancer.”

For the overnight fundraiser, participants had to form relay teams so they could take turns on the track throughout the entirety of the 24-hour charity drive. Prior to the event’s start, there were 119 online teams registered for the UCSB Relay for Life.

A highlight of the night, many relay participants said, was the ‘Ceremony of Hope’ at 9 p.m. The track was lined with illuminated bags of glow sticks spelling out messages that paid honor to cancer victims. A few cancer survivors then made speeches and joined to run a final lap.

T-cell lymphoma survivor Nick Galicia, a third-year business economics major, ran the remembrance lap on crutches due to a broken toe.

“Cancer never takes a break, so neither can I,” Galicia said.

Galicia, who was diagnosed with cancer in the second grade, said because the disease was the only thing he had known for so long, the idea of a “normal life” without it scared him.

“The thing I was most afraid of was that once the cancer was defeated, I would have a normal life and not be held back from school,” Galicia said.

Meanwhile, The Breast Cancer Resource Center of Santa Barbara collaborated with UCSB’s Hermanos Unidos to donate pink bands, with the proceeds going to cancer research.

Jose Delgado, community service chair for Hermanos Unidos, said it was important to provide emotional support to those suffering from the disease.

“As men of this university, we choose to endorse awareness of breast cancer so that women don’t feel alone in their struggle to overcome,” Delgado, a fourth-year Spanish and education major, said. “Even though this cancer does not affect us directly, we stand by them.”

According to the American Cancer Society web page, Relay for Life has had more than 3.5 million people from 4,900 communities around the world join the overnight event this year.

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May 17, 2009

Buying Viagra Online

Filed under: Drugs — Tags: , , — admin @ 4:12 am

First off all does Viagra really work ?
If it works then to what degree it works ? Is it good for all the aged people from above 18 ? All these questions would be there to a first time buyers . Its such a wide industry where this medications is sold at such a high quantity . We all wonder what would be the Viagra sales per day all around the world .
Again it’s a prescription drugs or non prescription drugs ?

Is buying Viagra online safe ?

Most of the Online Pharmacies around the world claim they are selling it authenticated Viagra Online . It would always be a debate to all Americans to choose one of the online pharmacies and go with them to buy Viagra online .

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May 15, 2009

Fewer than a third in U.S. would get swine flu jab

Filed under: Health Care — admin @ 11:47 am

WASHINGTON (Reuters) – Fewer than a third of U.S. adults would get a shot especially made to protect against the new H1N1 swine flu virus, according to a poll released on Thursday.

Most are simply not that worried about the new flu, which has spread around the globe, killed more than 60 people and brought the world to the brink of a pandemic, the poll of 1,442 adults found.

Only 36 percent said they got a vaccine against seasonal influenza this year, although virtually the whole population, especially everyone over 50, children, pregnant women and people with chronic conditions, are advised to get the immunization every year.

The World Health Organization estimates that seasonal flu is a factor in up to 500,000 deaths every year — 36,000 in the United States alone.

The poll by Zogby International and The University of Texas Health Science Center at Houston found that 38 percent not only were not vaccinated, but did not follow recommendations to wash or clean their hands frequently to prevent infection and were not restricting travel to Mexico.

Only 18 percent said the flu, which emerged in March, is a severe threat.

WHO officials will meet this week to decide whether to advise companies to go ahead and make a separate H1N1 vaccine to add to the vaccines being formulated to protect against seasonal influenza.

(Reporting by Maggie Fox, Editing by Sandra Maler)

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Pharmacies ask US to reassess CVS, Caremark merger

Filed under: Pharmacies — admin @ 11:39 am

By Diane Bartz

WASHINGTON, May 13 (Reuters) – An association representing independent pharmacies said it asked the U.S. Federal Trade Commission on Wednesday to reassess CVS’s (CVS.N) purchase of Caremark, saying CVS pushed up prices and used sensitive business information to poach customers from independents.

Representatives of the National Community Pharmacist Association, which has 23,000 member pharmacies, met with FTC Chairman Jon Leibowitz to discuss problems they said arose from the 2007 merger of drugstore company CVS with pharmacy benefit manager Caremark.

The group claimed that CVS pharmacy benefit managers steered patients to their own drugstores by raising co-pays for drugs bought elsewhere or by requiring that they be purchased at CVS.

Association president Holly Whitcomb Henry said on a media conference call that Leibowitz told them the issues were “of concern” and that FTC staff would look into them.

Henry said on the call that the pharmacies wanted a firewall between CVS’s retail pharmacy business and its pharmacy benefits business.

CVS, with more than 6,900 U.S. stores, could not be reached to comment on specific claims by the group, but had said prior to release of a statement by the group that the association had mischaracterized its business practices.

The FTC declined to comment.

Last week, the National Legislative Association on Prescription Drug Prices asked the FTC to take another look at its approval of CVS’s purchase of Caremark, saying there was evidence of “harmful and deceptive conduct.”

J.P. Morgan said in a research note on Wednesday that it disagreed with the independent pharmacists’ argument that CVS was restricting choice on the grounds that CVS does not dictate plan design.

Shares of CVS closed down 3.1 percent at $31.95 on the New York Stock Exchange trade. (Reporting by Diane Bartz)

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Drug Side Effects

Filed under: Drugs — admin @ 11:17 am

 

side effect is usually regarded as an undesirable secondary effect which occurs in addition to the desired therapeutic effect of a drug or medication. Side effects may vary for each individual depending on the person’s disease state, age, weight, gender, ethnicity and general health.

Side effects can occur when commencing, decreasing/increasing dosages, or ending a drug or medication regimen. Side effects may also lead to non-compliance with prescribed treatment. When side effects of a drug or medication are severe, the dosage may be adjusted or a second medication may be prescribed. Lifestyle or dietary changes may also help to minimize side effects.

Please note - many side effects may not be reported. Always consult your doctor orhealthcare specialist for medical advice. You may also report side effects to the FDA athttp://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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Drug Makers Try to Ease Recession’s Pain

Filed under: Drugs — Tags: — admin @ 7:33 am

Drug makers are expanding programs to help people afford medicines, amid a prolonged recession and efforts in Washington to overhaul the U.S. health-care system.

Pfizer Inc. said Thursday that it would provide more than 70 of its drugs for free to Americans who have lost their jobs since the beginning of the year and don’t have health insurance. Several other companies including Merck & Co., Abbott LaboratoriesAmgen Inc. and Wyeth, have expanded patient-assistance programs in recent weeks.

Pharmaceutical companies say helping people get access to medicines is the right thing to do. But there are other factors at play, too, industry watchers say. The programs could improve the industry’s standing in debates over various health-reform proposals—measures that could put pressure on drug prices. And the programs also can help companies sustain or boost market share by keeping patients on their drugs who will eventually regain insurance.

“Pharma’s obviously always trying to work on their image,” said Jon LeCroy, an analyst with Natixis Bleichroeder. “It gets them to be able to say, ‘We can help out in a recession and help people afford our drugs.’”

Pfizer, however, said its new program wasn’t motivated by political or business calculations. “This has to do with all of us seeing friends, relatives and neighbors going through tough economic times knowing we have medicines that are going to help them,” said spokesman Ray Kerins. He said the idea came recently from employees, who will be able to donate money to the program, which will be matched by a Pfizer foundation.

Ken Johnson, senior vice president at industry trade group PhRMA, said some manufacturers have had patient-assistance programs for decades. But over the past six month, there has been a 10%-to-15% increase in the number of people contacting a PhRMA clearinghouse program for information about assistance.

The new Pfizer program is open to Americans who have become unemployed since Jan. 1, and who lack prescription drug coverage. To be eligible, they must have been prescribed a Pfizer drug that they were taking for at least three months prior to losing their job and enrolling in the program, and must attest to financial hardship.

Those who qualify will receive Pfizer drugs for free for up to 12 months, or until they get insurance again. Included in the more than 70 primary-care medicines available through the program are Lipitor cholesterol-lowering pills and the Viagra anti-impotence pill. Specialty and oncology drugs, such as Sutent, aren’t part of the new program but have existing patient-assistance programs.

Abbott has expanded a co-pay assistance program for insured users of its anti-inflammatory drug Humira. A majority of Humira users now can have their monthly out-of-pocket costs limited to $5. The drug costs about $18,000 a year, on average. Abbott also has provided the drug for free to uninsured and low-income patients since its launch.

In March, Merck doubled the income limit for eligibility in its patient-assistance program to 400% of the federal poverty level. That amounts to about $88,200 or less for a family of four, and lesser amounts for couples and singles, including those who fall below these levels due to unemployment. Those eligible for Merck’s program can receive medicines for free.

Spokeswoman Amy Rose said participation in Merck’s patient-assistance program had declined in recent years due to patent expirations for some top-selling drugs, which resulted in cheaper generic options. Raising the income limit was a way to broaden participation and recognize difficult economic conditions.

Amgen and Wyeth became more generous with assistance for their Enbrel anti-inflammatory drug in mid-April, citing economic conditions. The plan increased coverage of patient co-pays—making them free for six months, and $10 or less per month thereafter for eligible patients.

In a conference call in late April, Amgen Chief Executive Kevin Sharer said Enbrel patients are having difficulty with co-pays, and “health and insurance coverage is not as broad or robust as in prior nonrecessionary years.”

Johnson & Johnson has had a comprehensive patient-assistance program in place for many years, said spokesman Greg Panico.

In some cases the patient-assistance programs offset sales, but analysts say the impact isn’t big. What’s more, even as they expand patient-assistance programs, some drug makers have continued to raise prices when possible. PhRMA’s Johnson noted that overall prescription drug-sales growth has slowed in recent years.

—Thomas Gryta contributed to this article.Write to Peter Loftus at peter.loftus@dowjones.com

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